2020 US Open – Wheelchair quad singles
| Wheelchair quad singles | |
|---|---|
| 2020 US Open | |
| Champion | Sam Schröder |
| Runner-up | Dylan Alcott |
| Score | 7–6(7–5), 0–6, 6–4 |
Sam Schröder defeated Dylan Alcott in the final, 7–6(7–5), 0–6, 6–4 to win the quad singles wheelchair tennis title at the 2020 US Open. Schröder had entered the tournament as a wildcard.
Andy Lapthorne was the defending champion, but was eliminated in the round-robin stage.