2021–22 CAF Confederation Cup

2021–22 CAF Confederation Cup
2021–22 TotalEnergies CAF Confederation Cup
Tournament details
DatesQualifying:
10 September 2021 – 6 February 2022
Competition proper:
13 February – 20 May 2022
TeamsCompetition proper: 16
Total: 51+16 (from 39 associations)
Final positions
Champions RS Berkane (2nd title)
Runners-up Orlando Pirates
Tournament statistics
Matches played61
Goals scored136 (2.23 per match)
Top scorer(s) Victorien Adebayor
(6 goals)
(Note: All statistics do not include qualifying play-offs)

The 2021–22 CAF Confederation Cup (officially the 2021–22 TotalEnergies CAF Confederation Cup for sponsorship reasons) was the 19th edition of Africa's secondary club football tournament organized by the Confederation of African Football (CAF) under the current CAF Confederation Cup title after the merger of CAF Cup and African Cup Winners' Cup.

The defending champions Raja Casablanca were unable to defend their title as they advanced to the group stage of the that season's CAF Champions League. The final was won by RS Berkane of Morocco 5–4 on penalties after a 1–1 draw after 120 minutes of regulation time against Orlando Pirates and RS Berkane at the Godswill Akpabio International Stadium in Uyo, Nigeria, capturing their second title in the process.

As winners, RS Berkane earned the right to play against the winners of the 2021–22 CAF Champions League, Wydad Casablanca, in the 2022 CAF Super Cup.