2021–22 Copa de la Reina de Fútbol
| Tournament details | |
|---|---|
| Country | Spain |
| Teams | 52 |
| Defending champions | Barcelona |
| Final positions | |
| Champions | Barcelona (9th title) |
| Runners-up | Sporting de Huelva |
| Tournament statistics | |
| Matches played | 40 |
| Goals scored | 123 (3.08 per match) |
| Top goal scorer(s) | Alexia Putellas (4 goals) |
| Awards | |
| Best player | María Pilar León |
The 2021–22 Copa de la Reina de Fútbol was the 40th edition of the Spanish women's association football national cup. Barcelona were the defending champions, having won the last two editions. They defended the title with a 6-1 win over Sporting de Huelva.