2021–22 NIFL Championship
| Season | 2021–22 | 
|---|---|
| Dates | 7 Aug 2021 – 30 Apr 2022 | 
| Champions | Newry City | 
| Promoted | Newry City | 
| Relegated | Queen's University | 
| Matches played | 228 | 
| Goals scored | 720 (3.16 per match) | 
| Biggest home win | Loughgall 12–1 Annagh United (30 April 2022)  | 
| Biggest away win | Knockbreda 1–6 Loughgall (11 September 2021)  | 
| Highest scoring | Loughgall 12–1 Annagh United (30 April 2022)  | 
← 2019–20  2022–23 →   | |
The 2021–22 NIFL Championship (known as the Lough 41 Championship for sponsorship reasons) was the fifth season of the NIFL Championship since gaining senior status. It is the second-tier of the Northern Ireland Football League - the national football league in Northern Ireland. The season began on 7 August 2021 and concluded on 30 April 2022.
The Championship returned after a one-year hiatus, following the cancellation of the 2020–21 season due to the COVID-19 pandemic in Northern Ireland.
Portadown were the champions from the 2019–20 season. However, as they won promotion to the 2020–21 NIFL Premiership before the COVID-19 hiatus, they could not defend their title. Newry City were confirmed as champions on the final day of the 2021–22 season.