2021–22 Tunisian Ligue Professionnelle 1
| Season | 2021–22 |
|---|---|
| Dates | 16 October 2021 – 26 June 2022 |
| Champions | Espérance de Tunis (32nd title) |
| Relegated | Espérance de Zarzis Club de Hammam-Lif |
| Champions League | Espérance de Tunis Union Monastirienne |
| Confederation Cup | Club Sfaxien Club Africain |
| Matches played | 156 |
| Goals scored | 265 (1.7 per match) |
| Top goalscorer | Mohamed Ali Ben Hammouda (10 goals) |
| Biggest home win | Espérance de Tunis 4–0 Club Bizertin (9 March 2022) |
| Biggest away win | Union de Ben Guerdane 1–5 Étoile du Sahel (29 April 2022) |
| Highest scoring | Union de Tataouine 5–3 Avenir de Rejiche (15 May 2022) |
| Longest winning run | Espérance de Tunis (4 matches) |
| Longest unbeaten run | Étoile du Sahel (11 matches) |
| Longest winless run | Union de Ben Guerdane (14 matches) |
| Longest losing run | Union de Ben Guerdane (6 matches) |
← 2020–21 2022–23 → | |
The 2021–22 Tunisian Ligue Professionnelle 1 (Tunisian Professional League) season was the 96th season of top-tier football in Tunisia.
Espérance de Tunis were the defending champions and successfully defended their title, winning their record-extending 6th consecutive title and 32nd title overall.
The VAR was used in the playoff.