2021 Chicago Marathon

43rd Chicago Marathon
Women's winner - Ruth Chepng'etich finished in 2:22:31
VenueChicago, United States
DatesOctober 10, 2021 (2021-10-10)
Champions
MenSeifu Tura (2:06:12)
WomenRuth Chepng'etich (2:22:31)
Wheelchair menDaniel Romanchuk (1:29:07)
Wheelchair womenTatyana McFadden (1:48:57)

The 2021 Chicago Marathon was held on October 10, 2021. It was the 43rd edition of the annual Chicago Marathon, and the first after the start of the COVID-19 pandemic in 2019. The 2020 Chicago Marathon was canceled as a result of the pandemic. The race was the third of five World Marathon Majors scheduled for 2021; all the events in the series took place in the span of six weeks between late September and early November.

Participants were required to provide proof of COVID-19 vaccination or a negative COVID-19 test taken within 72 hours of attending the event.

The marathon was won by Seifu Tura of Ethiopia and Ruth Chepng'etich of Kenya, in 2:06:12 and 2:22:31, respectively, while the wheelchair race was won by Daniel Romanchuk and Tatyana McFadden, both of the United States, in 1:29:07 and 1:48:57, respectively.