2021 Internationaux de Strasbourg – Singles
| Singles | |
|---|---|
| 2021 Internationaux de Strasbourg | |
| Champion | Barbora Krejčíková |
| Runner-up | Sorana Cîrstea |
| Score | 6–3, 6–3 |
| Draw | 32 |
| Seeds | 8 |
Elina Svitolina was the defending champion but chose not to participate.
Barbora Krejčíková won her maiden WTA singles title, defeating Sorana Cîrstea in the final, 6–3, 6–3.