2021 NCAA Division I men's lacrosse tournament
| 2021 NCAA Division I men's lacrosse tournament  | |||||
|---|---|---|---|---|---|
| Teams | 16 | ||||
| Finals site | Rentschler Field, East Hartford, Connecticut  | ||||
| Champions | Virginia (7th title) | ||||
| Runner-up | Maryland (15th title game) | ||||
| Semifinalists | North Carolina (14th Final Four) Duke (13th Final Four)  | ||||
| MOP | Connor Shellenberger | ||||
| Attendance | 14,816 finals | ||||
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The 2021 NCAA Division I Men's Lacrosse Championship was the 50th annual single-elimination tournament to determine the national championship for National Collegiate Athletic Association (NCAA) Division I men's college lacrosse. Because the Ivy League did not participate in lacrosse this season, no play-in game was required. This was the first tournament played since 2019 due to the 2020 tournament being cancelled during the COVID-19 pandemic.
Sixteen teams competed in the tournament based upon their performance during the regular season. For eight teams, entry into the tournament was by means of a conference tournament automatic qualifier and/or play in, while for the remaining eight teams at-large selection was determined by the NCAA selection committee.