2021 Prague Open – Singles

Singles
2021 Prague Open
Champion Barbora Krejčíková
Runner-up Tereza Martincová
Score6–2, 6–0
Draw32
Seeds8

Simona Halep was the defending champion, but chose not to participate.

Barbora Krejčíková won the title, defeating Tereza Martincová in the final, 6–2, 6–0.

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