2021 Uruguayan Segunda División season
| Season | 2021 |
|---|---|
| Champions | Albion (1st title) |
| Promoted | Albion Danubio Defensor Sporting |
| Relegated | Villa Teresa Rocha |
| Matches played | 115 |
| Goals scored | 256 (2.23 per match) |
← 2020 2022 → | |
The 2021 Uruguayan Segunda División was the season of second division professional of football in Uruguay. A total of 12 teams competed; the top two teams and the winner of the Championship play-offs were promoted to the Uruguayan Primera División.
On 19 March 2021, Nicolás Siri became the youngest hat-trick scorer in the history of Uruguayan football and the second in South America behind Pelé, after scoring a hat-trick in Danubio's 5–1 win against Boston River, at the age of 16 years and 11 months.