2022 ABN AMRO Rotterdam – Singles
| Singles | |
|---|---|
| 2022 ABN AMRO Rotterdam | |
| Champion | Félix Auger-Aliassime |
| Runner-up | Stefanos Tsitsipas |
| Score | 6–4, 6–2 |
| Draw | 32 (4 Q / 3 WC ) |
| Seeds | 8 |
Félix Auger-Aliassime defeated Stefanos Tsitsipas in the final, 6–4, 6–2. It was his maiden ATP Tour singles title, following eight runner-up finishes in prior finals.
Andrey Rublev was the defending champion, but lost in the semifinals to Auger-Aliassime. Rublev reached his 11th consecutive quarterfinal at an ATP 500 tournament.