2022 Citi Open – Men's singles
| Men's singles | |
|---|---|
| 2022 Citi Open | |
| Champion | Nick Kyrgios |
| Runner-up | Yoshihito Nishioka |
| Score | 6–4, 6–3 |
| Draw | 48 (6Q / 4WC) |
| Seeds | 16 |
Nick Kyrgios defeated Yoshihito Nishioka in the final, 6–4, 6–3 to win the men's singles tennis title at the 2022 Washington Open. It was his second Washington title, following 2019. Kyrgios saved five match points en route to the title, in the quarterfinals against Frances Tiafoe. He also did not drop serve during the tournament.
Jannik Sinner was the reigning champion, but did not compete.