2022 Hall of Fame Open – Singles
| Singles | |
|---|---|
| 2022 Hall of Fame Open | |
| Champion | Maxime Cressy |
| Runner-up | Alexander Bublik |
| Score | 2–6, 6–3, 7–6(7–3) |
| Draw | 28 (4 Q / 3 WC ) |
| Seeds | 8 |
Maxime Cressy defeated Alexander Bublik in the final, 2–6, 6–3, 7–6(7–3) to win the men's singles tennis title at the 2022 Hall of Fame Open. It was his maiden ATP Tour title.
Kevin Anderson was the reigning champion, but retired from professional tennis in May 2022.