2022 Italian Open – Women's singles

Defending champion Iga Świątek defeated Ons Jabeur in the final, 6–2, 6–2 to win the women's singles tennis title at the 2022 Italian Open. She did not drop a set during the tournament, and was the first player to win the title in Rome without dropping a set since Serena Williams in 2016. This was Świątek's fifth consecutive WTA Tour title, and she became the first player to win four WTA 1000 titles in a single season since Serena Williams in 2013. With the win, Świątek extended her winning streak to 28 matches – the longest on the WTA Tour since Serena Williams won 34 consecutive matches in 2013. This was also the first time in her professional career that Świątek defended a title. Jabeur was attempting to be the first player since Serena Williams in 2013 to win consecutive titles in Madrid and Rome; she reached the final after saving a match point in her semifinal match against Daria Kasatkina.