2022 Melbourne Summer Set 2 – Singles
| Singles | |
|---|---|
| 2022 Melbourne Summer Set 2 | |
| Champion | Amanda Anisimova |
| Runner-up | Aliaksandra Sasnovich |
| Score | 7–5, 1–6, 6–4 |
| Draw | 32 (6 Q / 3 WC ) |
| Seeds | 8 |
Amanda Anisimova defeated Aliaksandra Sasnovich in the final, 7–5, 1–6, 6–4 to win the singles title at the 2022 Melbourne Summer Set 2.
This was the first edition of the tournament.