2022 US Open – Wheelchair men's doubles
| Wheelchair men's doubles | |
|---|---|
| 2022 US Open | |
| Champions | Martín de la Puente Nicolas Peifer |
| Runners-up | Alfie Hewett Gordon Reid |
| Score | 4–6, 7–5, [10–6] |
Martín de la Puente and Nicolas Peifer defeated the five-time defending champions Alfie Hewett and Gordon Reid in the final, 4–6, 7–5, [10–6] to win the men's doubles wheelchair tennis title at the 2022 US Open. It was de la Puente's maiden major title, and Peifer's eighth in doubles.