2023 Internazionali Femminili di Palermo – Singles
| Singles | |
|---|---|
| 2023 Internazionali Femminili di Palermo | |
| Champion | Zheng Qinwen |
| Runner-up | Jasmine Paolini |
| Score | 6–4, 1–6, 6–1 |
| Draw | 32 |
| Seeds | 8 |
Zheng Qinwen defeated Jasmine Paolini in the final, 6–4, 1–6, 6–1 to win the singles tennis title at the 2023 Internazionali Femminili di Palermo. It was Zheng's first WTA Tour singles title, and she was the first Chinese player to win the singles title at Palermo.
Irina-Camelia Begu was the reigning champion, but she chose to compete at the WTA 125 event in Iași instead.