2023 Italian Open – Women's singles

Women's singles
2023 Italian Open
Champion Elena Rybakina
Runner-up Anhelina Kalinina
Score6–4, 1–0, ret.
Draw96 (12 Q / 8 WC )
Seeds32

Elena Rybakina won the women's singles tennis title at the 2023 Italian Open after Anhelina Kalinina retired from the final with the scoreline at 6–4, 1–0. It was Rybakina's second career WTA 1000 title. Rybakina won three of her six matches at the tournament via retirement: over Anna Kalinskaya in the third round, Iga Świątek in the quarterfinals, and Kalinina in the final. With the win, Rybakina entered the top five in the WTA rankings for the first time at world No. 4.

Świątek was the two-time defending champion, but retired in the quarterfinals against Rybakina due to a hip injury. Świątek was attempting to be the first woman to win three consecutive titles in Rome since Conchita Martínez in 1995.