2024–25 Louisville Cardinals women's basketball team

The 2024–25 Louisville Cardinals women's basketball team represented the University of Louisville during the 2024–25 NCAA Division I women's basketball season. The Cardinals were led by eighteenth-year head coach Jeff Walz, and played their home games at the KFC Yum! Center in Louisville, Kentucky. This season was their eleventh year competing in the Atlantic Coast Conference.

The Cardinals beagan the season ranked seventeenth in the AP poll and traveled to France to play fifth-ranked UCLA in the Aflac Oui-Play event. The Cardinals lost the game 66–59. They won two games before losing to rival and twentieth-ranked Kentucky 71–61 in overtime. The Cardinals dropped to number twenty five in the polls before winning three straight games to bounce back up to twenty second. They lost in the ACC–SEC Challenge to eleventh-ranked Oklahoma 78–72. They followed that game with a 85–52 loss to second-ranked Connecticut in the Women's Champions Classic. They won one game before losing their ACC opener, and the Jimmy V Classic to twenty second-ranked NC State 72–42. The Cardinals' inconsistency improved after that as they went on a seven-game winning streak. The streak included an overtime win over Wake Forest and a 69–60 win over thirteenth ranked Georgia Tech. The streak was ended with a 70–65 loss at Virginia Tech. The Cardinals went 6–1 over their next seven games, with the only loss being a 89–71 defeat against number three Notre Dame. During this stretch they defeated three ranked team: number twenty one California, number twenty three Florida State and number eleven Duke. They faced two ranked teams in their final three games, and lost to both. They lost 79–75 to ninth-ranked North Carolina and 72–59 in a rematch against number three Notre Dame. They moved to twenty fifth in the rankings after the North Carolina loss, but dropped out in the first post-season ranking.

The Cardinals finished the season 22–11 overall and 13–5 in ACC play to finish in a three-way tie for fourth place. As the sixth seed in the ACC tournament, earned a bye into the second round where they defeated Clemson 70–68 in overtime. They lost to eleventh ranked and third seed Duke 61–48 in the Quarterfinals. They received an at-large invitation to the NCAA tournament and were the seven-seed in the Birmingham 3 region. They defeated ten seed Nebraska in the First Round before losing to second seed and sixth ranked TCU 85–70 in the Second Round to end their season.