2025 Abierto Mexicano Telcel – Singles
| Singles | |
|---|---|
| 2025 Abierto Mexicano Telcel | |
| Champion | Tomáš Macháč |
| Runner-up | Alejandro Davidovich Fokina |
| Score | 7–6(8–6), 6–2 |
| Draw | 32 (4 Q / 3 WC ) |
| Seeds | 8 |
Tomáš Macháč defeated Alejandro Davidovich Fokina in the final, 7–6(8–6), 6–2, to win the singles title at the 2025 Abierto Mexicano Telcel. It was his first ATP Tour title.
Alex de Minaur was the two-time reigning champion, but chose to compete in Dubai instead.