2025 Challenger Città di Lugano – Singles

Singles
2025 Challenger Città di Lugano
Champion Borna Ćorić
Runner-up Raphaël Collignon
Score6–3, 6–1

Otto Virtanen was the defending champion but chose not to defend his title.

Borna Ćorić won the title after defeating Raphaël Collignon 6–3, 6–1 in the final.