2025 Cleveland Open – Singles

Singles
2025 Cleveland Open
Champion Colton Smith
Runner-up Eliot Spizzirri
Score6–4, 6–7(6–8), 6–3

Patrick Kypson was the defending champion but chose not to defend his title.

Colton Smith won the title after defeating Eliot Spizzirri 6–4, 6–7(6–8), 6–3 in the final.