2025 French Open – Women's singles

Coco Gauff defeated Aryna Sabalenka in the final, 6–7^(5–7), 6–2, 6–4 to win the women's singles tennis title at the 2025 French Open. It was her first French Open singles title and second major singles title overall. Gauff was the first American to win the title since Serena Williams in 2015. It was the first French Open final between the world No. 1 and 2 since 2013, and the first at any major since the 2018 Australian Open. Sabalenka was the first woman to reach the final of three consecutive majors since Williams in 2016.

Iga Świątek was the three-time defending champion, but lost in the semifinals to Sabalenka. The defeat ended her 26-match win streak in the event, second only to Chris Evert's 29 consecutive wins.

Ranked No. 361, Loïs Boisson was the first Frenchwoman to reach the singles semifinals of the French Open since Marion Bartoli in 2011, and the first wildcard to do so in the Open Era. Boisson was only the third woman in the Open Era to reach the semifinals of a major on her singles main-draw debut, after Monica Seles and Jennifer Capriati at the 1989 and 1990 French Opens, respectively. With her first-round win, Victoria Azarenka became the oldest woman to score a double bagel in a singles major main-draw match in the Open Era. She also became the first woman to achieve the feat in three different decades.

This marked the final French Open appearance of former world No. 4 and two-time doubles champion Caroline Garcia. She lost in the first round to Bernarda Pera. Former world No. 5 and 2012 finalist Sara Errani played her last professional singles match, losing in the second round of qualifying to Anna-Lena Friedsam.