2025 Hamburg Open – Men's singles
| Men's singles | |
|---|---|
| 2025 Hamburg Open | |
| Champion | Flavio Cobolli |
| Runner-up | Andrey Rublev |
| Score | 6–2, 6–4 |
| Draw | 32 (4Q / 3WC) |
| Seeds | 8 |
Flavio Cobolli defeated Andrey Rublev in the final, 6–2, 6–4 to win the men's singles tennis title at the 2025 Hamburg Open. It was his second ATP Tour title and first ATP 500 title.
Arthur Fils was the reigning champion, but did not participate this year.