25CN-NBOH

25CN-NBOH
Clinical data
Other namesNBOH-2C-CN
Drug classSelective serotonin 5-HT2A receptor agonist
Legal status
Legal status
Identifiers
  • 4-[2-[(2-hydroxyphenyl)methylamino]ethyl]-2,5-dimethoxybenzonitrile
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC18H20N2O3
Molar mass312.369 g·mol−1
3D model (JSmol)
  • COc1cc(C#N)c(OC)cc1CCNCc2ccccc2O
  • InChI=1S/C18H20N2O3/c1-22-17-10-15(11-19)18(23-2)9-13(17)7-8-20-12-14-5-3-4-6-16(14)21/h3-6,9-10,20-21H,7-8,12H2,1-2H3
  • Key:VWEDZTZAXHMZIL-UHFFFAOYSA-N

25CN-NBOH, also known as NBOH-2C-CN, is a compound indirectly derived from the phenethylamine series of hallucinogens, which was discovered in 2014 at the University of Copenhagen. It is a member of the NBOMe family of psychedelics.

The drug is notable in being one of the most selective agonists of the serotonin 5-HT2A receptor known.

A tritiated version of 25CN-NBOH has also been accessed and used for more detailed investigations of the binding to serotonin 5-HT2 receptors and autoradiography.