2C-TFM

2C-TFM
Clinical data
Other names2C-CF3; 2,5-Dimethoxy-4-trifluoromethylphenethylamine; 4-Trifluoromethyl-2,5-dimethoxyphenethylamine
Routes of
administration
Oral
Drug classSerotonin 5-HT2 receptor agonist; Serotonergic psychedelic; Hallucinogen
Pharmacokinetic data
Duration of action≥5–10 hours
Identifiers
  • 2-[2,5-dimethoxy-4-(trifluoromethyl)phenyl]ethan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H14F3NO2
Molar mass249.233 g·mol−1
3D model (JSmol)
Melting point260 °C (500 °F) (hydrochloride)
  • FC(F)(C1=C(OC)C=C(CCN)C(OC)=C1)F
  • InChI=1S/C11H14F3NO2/c1-16-9-6-8(11(12,13)14)10(17-2)5-7(9)3-4-15/h5-6H,3-4,15H2,1-2H3 Y
  • Key:LYXGNMLWYONZID-UHFFFAOYSA-N Y
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2C-TFM, also known as 4-trifluoromethyl-2,5-dimethoxyphenethylamine, is a serotonin 5-HT2 receptor agonist and psychedelic drug of the phenethylamine and 2C families. It has also been called 2C-CF3, a name derived from the para-trifluoromethyl group it contains. The drug was first synthesized in the laboratory of David E. Nichols. Later, it was tried humans and its psychedelic effects were confirmed. 2C-TFM is the most potent psychedelic of the 2C psychedelics, with an active dosage of 3 to 6 mg orally.