2nd Maryland Infantry Regiment

2nd Maryland Infantry Regiment may refer to:

• 2nd Maryland Regiment, a unit during the American Revolution
• 2nd Maryland Infantry Regiment (Confederate), a regiment in the Confederate States Army
• 2nd Maryland Infantry Regiment (Union), a regiment in the Union army
• 2nd Maryland Infantry Regiment, Potomac Home Brigade, a regiment in the Union army
• 2nd Maryland Infantry, Eastern Shore, a regiment in the Union army