3,4-Dihydroxyphenylacetaldehyde

3,4-Dihydroxyphenylacetaldehyde
Names
Preferred IUPAC name
(3,4-Dihydroxyphenyl)acetaldehyde
Other names
DOPAL; 2-(3,4-Dihydroxyphenyl)acetaldehyde; Dopaldehyde; Dopamine aldehyde
Identifiers
3D model (JSmol)
Abbreviations DOPAL
ChEBI
ChemSpider
ECHA InfoCard 100.237.172
KEGG
MeSH 3,4-dihydroxyphenylacetaldehyde
UNII
  • InChI=1S/C8H8O3/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,4-5,10-11H,3H2 Y
    Key: IADQVXRMSNIUEL-UHFFFAOYSA-N Y
  • InChI=1/C8H8O3/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,4-5,10-11H,3H2
    Key: IADQVXRMSNIUEL-UHFFFAOYAV
  • Oc1ccc(CC=O)cc1O
  • OC1=CC=C(CC=O)C=C1O
Properties
C8H8O3
Molar mass 152.149 g·mol−1
Density 1.306 g/mL
Boiling point 351 °C (664 °F; 624 K)
Related compounds
Related 2-phenyl aldehydes
 Phenylacetaldehyde

Phenylglyoxal

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

3,4-Dihydroxyphenylacetaldehyde (DOPAL), also known as dopamine aldehyde, is a metabolite of the monoamine neurotransmitter dopamine formed by monoamine oxidase (MAO).

Other metabolic pathways of dopamine metabolism include methylation by catechol O-methyltransferase (COMT) into 3-methoxytyramine and β-hydroxylation by dopamine β-hydroxylase (DBH) into norepinephrine. There is also spontaneous oxidation of dopamine into dopamine quinones and reactive oxygen species.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.