3-Methylhistidine

3-Methylhistidine
Names
	Systematic IUPAC name (2S)-2-Amino-3-(1-methyl-1H-imidazol-5-yl)propanoic acid
Identifiers
CAS Number	368-16-1 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	83651
ChEBI	CHEBI:27596;
ChEMBL	ChEMBL3251670;
ChemSpider	58494;
ECHA InfoCard	100.006.095
EC Number	206-704-6;
Gmelin Reference	1568650
KEGG	C01152;
PubChem CID	64969;
UNII	MEH8O8Y0H0 ;
CompTox Dashboard (EPA)	DTXSID90920521 ;
	InChI InChI=1S/C7H11N3O2/c1-10-4-9-3-5(10)2-6(8)7(11)12/h3-4,6H,2,8H2,1H3,(H,11,12)/t6-/m0/s1 Key: JDHILDINMRGULE-LURJTMIESA-N;
	SMILES CN1C=NC=C1CC(C(=O)O)N;
Properties
Chemical formula	C7H11N3O2
Molar mass	169.184
Solubility in water	200 mg/mL at 25 °C
Hazards
	GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H315, H319, H335
Precautionary statements	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

3-Methylhistidine (3-MH) is a post-translationally modified amino acid which is excreted in human urine. Urinary concentration of 3-methylhistidine is a biomarker for skeletal muscle protein breakdown in humans who have been subject to muscle injury. Urinary 3-methylhistidine concentrations are also elevated from consumption of soy-based products and meat, particularly chicken.