5-Fluoro-AMT

5-Fluoro-AMT
Clinical data
Other names5-Fluoro-α-methyltryptamine; 5-Fluoro-alpha-methyltryptamine; 5-Fluoro-αMT; 5-Fluoro-AMT; 5F-AMT; PAL-212; PAL-544
Routes of
administration
Oral
Drug classSerotonin receptor agonist; Serotonin 5-HT2A receptor agonist; Serotonin–norepinephrine–dopamine releasing agent; Serotonergic psychedelic; Hallucinogen; Stimulant; Entactogen
Identifiers
  • 1-(5-fluoro-1H-indol-3-yl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H13FN2
Molar mass192.237 g·mol−1
3D model (JSmol)
  • Fc1cc2c(cc1)[nH]cc2CC(N)C
  • InChI=1S/C11H13FN2/c1-7(13)4-8-6-14-11-3-2-9(12)5-10(8)11/h2-3,5-7,14H,4,13H2,1H3 Y
  • Key:CTGFDWBZMCPVED-UHFFFAOYSA-N Y
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5-Fluoro-αMT, also known as 5-fluoro-α-methyltryptamine (5F-AMT) or as PAL-212 or PAL-544, is a monoaminergic drug of the tryptamine and α-alkyltryptamine families related to α-methyltryptamine (αMT).

The drug is known to act as a serotonin receptor agonist, monoamine releasing agent, and potent monoamine oxidase inhibitor. It produces psychedelic- and stimulant-like effects in animals. 5-Fluoro-AMT is also known to be psychoactive in humans, though its effects have not been well-described.

5-Fluoro-AMT was first described in the scientific literature by 1963. There has been interest in 5-fluoro-AMT as a possible treatment for cocaine dependence.