6-Hydroxymelatonin

6-Hydroxymelatonin
Names
	Preferred IUPAC name N-[2-(6-Hydroxy-5-methoxy-1H-indol-3-yl)ethyl]acetamide
	Other names 6-Oxymelatonin
Identifiers
CAS Number	2208-41-5 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:198;
ChemSpider	1794;
ECHA InfoCard	100.164.426
KEGG	C05643;
PubChem CID	1864;
UNII	TV437T5077 ;
CompTox Dashboard (EPA)	DTXSID00176577 ;
	InChI InChI=1S/C13H16N2O3/c1-8(16)14-4-3-9-7-15-11-6-12(17)13(18-2)5-10(9)11/h5-7,15,17H,3-4H2,1-2H3,(H,14,16) Key: OMYMRCXOJJZYKE-UHFFFAOYSA-N; InChI=1/C13H16N2O3/c1-8(16)14-4-3-9-7-15-11-6-12(17)13(18-2)5-10(9)11/h5-7,15,17H,3-4H2,1-2H3,(H,14,16) Key: OMYMRCXOJJZYKE-UHFFFAOYAK;
	SMILES CC(=O)NCCC1=CNC2=CC(=C(C=C21)OC)O;
Properties
Chemical formula	C13H16N2O3
Molar mass	248.282 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

6-Hydroxymelatonin (6-OHM) is a naturally occurring, endogenous, major active metabolite of melatonin. 6-Hydroxymelatonin is produced as a result of the enzymatic conversion of melatonin through hydroxylation. Similar to melatonin, 6-OHM is a full agonist of the MT₁ and MT₂ receptors. It is also an antioxidant and neuroprotective, and is even more potent in this regard relative to melatonin.