Alpha-1-B glycoprotein

A1BG
Identifiers
Aliases	A1BG, A1B, ABG, GAB, HYST2477, alpha-1-B glycoprotein
External IDs	OMIM: 138670; MGI: 2152878; HomoloGene: 11167; GeneCards: A1BG; OMA:A1BG - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	58,353,492 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	60,794,861 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; anterior pituitary; ; C1 segment; ; canal of the cervix; ; right coronary artery; ; putamen; ; nucleus accumbens; ; Amygdala; ; right auricle of heart; ; hippocampus proper;
	Top expressed in
	primary oocyte; ; zygote; ; secondary oocyte; ; neural layer of retina; ; muscle of thigh; ; spermatid; ; quadriceps femoris muscle; ; skeletal muscle tissue; ; Hypothalamus; ; blastocyst;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function;
Cellular component	blood microparticle; extracellular exosome; extracellular region; platelet alpha granule lumen; extracellular space; secretory granule lumen; ficolin-1-rich granule lumen; extracellular matrix; collagen-containing extracellular matrix;
Biological process	platelet degranulation; neutrophil degranulation; biological process;
	Sources:Amigo / QuickGO
Orthologs
	1
	117586
	ENSG00000121410
	ENSMUSG00000022347
	P04217
	Q19LI2
	NM_130786
	NM_001081067
	NP_570602
	NP_001074536
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-1-B glycoprotein is a 54.3 kDa protein in humans that is encoded by the A1BG gene. The protein encoded by this gene is a plasma glycoprotein of unknown function. The protein shows sequence similarity to the variable regions of some immunoglobulin supergene family member proteins. Patients who have pancreatic ductal adenocarcinoma show an overexpression of A1BG in pancreatic juice.