Aladin (protein)

AAAS
Identifiers
Aliases	AAAS, AAA, AAASb, ADRACALA, ADRACALIN, ALADIN, GL003, aladin WD repeat nucleoporin
External IDs	OMIM: 605378; MGI: 2443767; HomoloGene: 9232; GeneCards: AAAS; OMA:AAAS - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	53,324,864 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	102,259,206 bp
RNA expression pattern
	Top expressed in
	right adrenal cortex; ; right uterine tube; ; anterior pituitary; ; left adrenal cortex; ; apex of heart; ; right testis; ; ganglionic eminence; ; left testis; ; muscle layer of sigmoid colon; ; ventricular zone;
	Top expressed in
	tail of embryo; ; yolk sac; ; genital tubercle; ; embryo; ; morula; ; blastocyst; ; spermatocyte; ; spermatid; ; embryo; ; epiblast;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	molecular function;
Cellular component	centrosome; nuclear membrane; nuclear envelope; membrane; nuclear pore; nucleoplasm; nucleus; cytosol; host cell; spindle pole; mitotic spindle; cytoplasm; cytoskeleton;
Biological process	regulation of nucleocytoplasmic transport; mRNA transport; viral transcription; learning; protein sumoylation; mitotic nuclear membrane disassembly; nucleocytoplasmic transport; regulation of cellular response to heat; protein transport; fertilization; viral process; intracellular transport of virus; tRNA export from nucleus; mRNA export from nucleus; regulation of gene silencing by miRNA; regulation of glycolytic process; transport; microtubule bundle formation; mitotic spindle assembly;
	Sources:Amigo / QuickGO
Orthologs
	8086
	223921
	ENSG00000094914
	ENSMUSG00000036678
	Q9NRG9
	P58742
	NM_001173466; NM_015665
	NM_153416
	NP_001166937; NP_056480
	NP_700465
	Wikidata
View/Edit Human	View/Edit Mouse

Aladin, also known as adracalin, is a nuclear envelope protein that in humans is encoded by the AAAS gene. It is named after the achalasia–addisonianism–alacrima syndrome (triple A syndrome) which occurs when the gene is mutated.