ABCA8

ABCA8
Identifiers
Aliases	ABCA8, ATP binding cassette subfamily A member 8
External IDs	OMIM: 612505; MGI: 1351668; HomoloGene: 56029; GeneCards: ABCA8; OMA:ABCA8 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	68,955,392 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	109,886,671 bp
RNA expression pattern
	Top expressed in
	spinal ganglia; ; trigeminal ganglion; ; parietal pleura; ; pericardium; ; tibial nerve; ; cardiac muscle tissue of right atrium; ; germinal epithelium; ; corpus callosum; ; sural nerve; ; vena cava;
	Top expressed in
	lumbar spinal ganglion; ; muscle of thigh; ; liver; ; neural layer of retina; ; left lobe of liver; ; dentate gyrus of hippocampal formation granule cell; ; esophagus; ; extraocular muscle; ; upper arm; ; triceps brachii muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; ATPase activity; ATP binding; ABC-type xenobiotic transporter activity; ATPase-coupled transmembrane transporter activity; lipid transporter activity;
Cellular component	integral component of membrane; plasma membrane; membrane; mitochondrial inner membrane; intracellular membrane-bounded organelle;
Biological process	lipid transport; xenobiotic transport; xenobiotic transmembrane transport; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	10351
	27404
	ENSG00000141338
	ENSMUSG00000020620
	O94911
	Q8K440
	NM_001288985; NM_001288986; NM_007168; NM_001375771; NM_001375772
	NM_013851; NM_001362749
	NP_001275914; NP_001275915; NP_009099; NP_001362700; NP_001362701
	NP_038879; NP_001349678
	Wikidata
View/Edit Human	View/Edit Mouse

ABC-type organic anion transporter ABCA8 is a protein that in humans is encoded by the ABCA8 gene.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. This protein is a member of the ABCA subfamily. Members of the ABCA subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes.