ABCB9

ABCB9
Identifiers
AliasesABCB9, EST122234, TAPL, ATP binding cassette subfamily B member 9
External IDsOMIM: 605453; MGI: 1861729; HomoloGene: 10491; GeneCards: ABCB9; OMA:ABCB9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

23457

56325

Ensembl

ENSG00000150967

ENSMUSG00000029408

UniProt

Q9NP78

Q9JJ59

RefSeq (mRNA)

NM_019875

RefSeq (protein)

NP_001229942
NP_001229943
NP_062570
NP_062571
NP_982269

NP_063928

Location (UCSC)Chr 12: 122.92 – 122.98 MbChr 5: 124.2 – 124.23 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

ATP-binding cassette sub-family B member 9 is a protein that in humans is encoded by the ABCB9 gene.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.