ABCC10

ABCC10
Identifiers
AliasesABCC10, EST182763, MRP7, SIMRP7, ATP binding cassette subfamily C member 10
External IDsOMIM: 612509; MGI: 2386976; HomoloGene: 58616; GeneCards: ABCC10; OMA:ABCC10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

89845

224814

Ensembl

ENSG00000124574

ENSMUSG00000032842

UniProt

Q5T3U5

Q8R4P9

RefSeq (mRNA)

NM_001198934
NM_033450
NM_001350518

NM_145140
NM_170680
NM_001347396

RefSeq (protein)

NP_001185863
NP_258261
NP_001337447

NP_001334325
NP_660122
NP_733780

Location (UCSC)Chr 6: 43.43 – 43.45 MbChr 17: 46.61 – 46.64 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Multidrug resistance-associated protein 7 is a protein that in humans is encoded by the ABCC10 gene.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.