ABCC11

ABCC11
Identifiers
Aliases	ABCC11, ATP-binding cassette, sub-family C (CFTR/MRP), member 11, EWWD, MRP8, WW, ATP binding cassette subfamily C member 11, ATP-binding cassette transporter sub-family C member 1
External IDs	OMIM: 607040; HomoloGene: 69511; GeneCards: ABCC11; OMA:ABCC11 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	48,247,568 bp
RNA expression pattern
	Top expressed in
	testicle; ; right lobe of liver; ; gonad; ; left testis; ; right uterine tube; ; right testis; ; sural nerve; ; prefrontal cortex; ; epithelium of lactiferous gland; ; lactiferous duct;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; organic anion transmembrane transporter activity; ATPase activity; ATP binding; purine nucleotide transmembrane transporter activity; ATPase-coupled inorganic anion transmembrane transporter activity; ATPase-coupled transmembrane transporter activity;
Cellular component	integral component of membrane; integral component of plasma membrane; extracellular exosome; membrane; vacuole; vacuolar membrane; plasma membrane; cytoplasmic vesicle membrane; cytoplasmic vesicle;
Biological process	purine nucleotide transport; transmembrane transport; organic anion transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	85320
	n/a
	ENSG00000121270
	n/a
	Q96J66
	n/a
	NM_032583; NM_033151; NM_145186; NM_001370496; NM_001370497
	n/a
NP_115972; NP_149163; NP_660187; NP_001357425; NP_001357426;
	NP_115972.2; NP_149163.2
	n/a
	Wikidata
View/Edit Human

ATP-binding cassette transporter sub-family C member 11, also MRP8 (Multidrug Resistance-Related Protein 8), is a membrane transporter that exports certain molecules from inside a cell. It is a protein that in humans is encoded by gene ABCC11.

The gene is responsible for determination of human cerumen type (wet or dry ear wax) and presence of underarm osmidrosis (odor associated with sweat caused by apocrine secretion), and is associated with colostrum secretion.