ABCG1

ABCG1
Identifiers
Aliases	ABCG1, ABC8, WHITE1, ATP binding cassette subfamily G member 1
External IDs	OMIM: 603076; MGI: 107704; HomoloGene: 21022; GeneCards: ABCG1; OMA:ABCG1 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	42,297,244 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	31,336,962 bp
RNA expression pattern
	Top expressed in
	right adrenal gland; ; left adrenal gland; ; right adrenal cortex; ; jejunal mucosa; ; left adrenal cortex; ; spleen; ; Skeletal muscle tissue of rectus abdominis; ; lower lobe of lung; ; amniotic fluid; ; internal globus pallidus;
	Top expressed in
	globus pallidus; ; right lung lobe; ; olfactory tubercle; ; stria vascularis; ; dorsal striatum; ; medial dorsal nucleus; ; median eminence; ; arcuate nucleus; ; olfactory epithelium; ; lateral geniculate nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein dimerization activity; protein homodimerization activity; ADP binding; phospholipid transporter activity; ABC-type sterol transporter activity; cholesterol binding; ATPase activity; toxin transmembrane transporter activity; protein binding; protein heterodimerization activity; phospholipid binding; ATP binding; cholesterol transfer activity; ATPase-coupled transmembrane transporter activity;
Cellular component	integral component of membrane; recycling endosome; endosome; Golgi apparatus; endoplasmic reticulum membrane; membrane; Golgi membrane; plasma membrane; integral component of plasma membrane; endoplasmic reticulum; mitochondrion; external side of plasma membrane;
Biological process	phospholipid homeostasis; lipid transport; regulation of transcription, DNA-templated; detection of hormone stimulus; phospholipid efflux; glycoprotein transport; cholesterol transport; cholesterol metabolic process; response to organic substance; negative regulation of cholesterol storage; response to lipid; intracellular cholesterol transport; low-density lipoprotein particle remodeling; positive regulation of cholesterol efflux; transmembrane transport; cholesterol efflux; positive regulation of cholesterol biosynthetic process; negative regulation of lipid storage; cholesterol homeostasis; regulation of cholesterol esterification; negative regulation of macrophage derived foam cell differentiation; amyloid precursor protein catabolic process; reverse cholesterol transport; toxin transport; high-density lipoprotein particle remodeling; transport; cellular response to high density lipoprotein particle stimulus; positive regulation of protein secretion; positive regulation of amyloid-beta formation;
	Sources:Amigo / QuickGO
Orthologs
	9619
	11307
	ENSG00000160179
	ENSMUSG00000024030
	P45844
	Q64343
NM_004915; NM_016818; NM_207174; NM_207627; NM_207628;
	NM_207629; NM_207630
	NM_009593
NP_004906; NP_058198; NP_997057; NP_997510; NP_997511;
	NP_997512
	NP_033723
	Wikidata
View/Edit Human	View/Edit Mouse

ATP-binding cassette sub-family G member 1 is a protein that in humans is encoded by the ABCG1 gene. It is a homolog of the well-known Drosophila gene white.