ABI1

ABI1
Identifiers
Aliases	ABI1, ABI-1, ABLBP4, E3B1, NAP1BP, SSH3BP, SSH3BP1, abl interactor 1
External IDs	OMIM: 603050; MGI: 104913; HomoloGene: 38053; GeneCards: ABI1; OMA:ABI1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	26,861,087 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	22,930,253 bp
RNA expression pattern
	Top expressed in
	epithelium of nasopharynx; ; amniotic fluid; ; palpebral conjunctiva; ; cartilage tissue; ; oral cavity; ; bronchial epithelial cell; ; skin of arm; ; bone marrow; ; thymus; ; mucosa of paranasal sinus;
	Top expressed in
	mesenteric lymph nodes; ; subiculum; ; granulocyte; ; lateral septal nucleus; ; left lung lobe; ; parotid gland; ; lobe of cerebellum; ; skin of external ear; ; anterior amygdaloid area; ; ventral tegmental area;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein tyrosine kinase activator activity; protein-containing complex binding; cytoskeletal protein binding; protein binding; SH3 domain binding; cadherin binding;
Cellular component	cytoplasm; cytosol; postsynaptic membrane; cell projection; postsynaptic density; SCAR complex; membrane; filopodium; growth cone; plasma membrane; synapse; intracellular anatomical structure; cell junction; cell leading edge; endoplasmic reticulum; neuron projection; extracellular exosome; cytoskeleton; nucleus; lamellipodium; filopodium tip;
Biological process	somitogenesis; megakaryocyte development; Fc-gamma receptor signaling pathway involved in phagocytosis; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of protein tyrosine kinase activity; vascular endothelial growth factor receptor signaling pathway; peptidyl-tyrosine phosphorylation; viral process; lamellipodium morphogenesis; negative regulation of cell population proliferation; dendrite morphogenesis; actin polymerization or depolymerization;
	Sources:Amigo / QuickGO
Orthologs
	10006
	11308
	ENSG00000136754
	ENSMUSG00000058835
	Q8IZP0
	Q8CBW3
NM_001012750; NM_001012751; NM_001012752; NM_001178116; NM_001178119;
	NM_001178120; NM_001178121; NM_001178122; NM_001178123; NM_001178124; NM_001178125; NM_005470; NM_001348029; NM_001348030; NM_001348031; NM_001348032; NM_001348033; NM_001348034
NM_001077190; NM_001077192; NM_001077193; NM_007380; NM_145994;
	NM_001331043; NM_001331044; NM_001331045; NM_001377510; NM_001377511; NM_001377512; NM_001377513
NP_001012768; NP_001012769; NP_001012770; NP_001171587; NP_001171590;
	NP_001171591; NP_001171592; NP_001171593; NP_001171594; NP_001171595; NP_001171596; NP_005461; NP_001334958; NP_001334959; NP_001334960; NP_001334961; NP_001334962; NP_001334963
NP_001070658; NP_001070660; NP_001070661; NP_001317972; NP_001317973;
	NP_001317974; NP_031406; NP_666106; NP_001364439; NP_001364440; NP_001364441; NP_001364442
	Wikidata
View/Edit Human	View/Edit Mouse

Abl interactor 1 also known as Abelson interactor 1 (Abi-1) is a protein that in humans is encoded by the ABI1 gene.