ACAT1

ACAT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F2S, 2IB7, 2IB8, 2IB9, 2IBU, 2IBW, 2IBY
Identifiers
Aliases	ACAT1, ACAT, MAT, T2, THIL, acetyl-CoA acetyltransferase 1
External IDs	OMIM: 607809; MGI: 87870; HomoloGene: 6; GeneCards: ACAT1; OMA:ACAT1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	108,147,776 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	53,521,682 bp
RNA expression pattern
	Top expressed in
	kidney tubule; ; Skeletal muscle tissue of rectus abdominis; ; renal medulla; ; right lobe of liver; ; right ventricle; ; Skeletal muscle tissue of biceps brachii; ; thoracic diaphragm; ; muscle of thigh; ; myocardium of left ventricle; ; apex of heart;
	Top expressed in
	Paneth cell; ; atrioventricular valve; ; ureter; ; proximal tubule; ; hair follicle; ; medullary collecting duct; ; left lobe of liver; ; myocardium of ventricle; ; condyle; ; trigeminal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; protein homodimerization activity; acyltransferase activity, transferring groups other than amino-acyl groups; metal ion binding; catalytic activity; enzyme binding; acyltransferase activity; carbon-carbon lyase activity; ligase activity, forming carbon-carbon bonds; acetyl-CoA C-acetyltransferase activity; acetyl-CoA C-acyltransferase activity; C-acetyltransferase activity;
Cellular component	mitochondrial matrix; mitochondrial inner membrane; extracellular exosome; mitochondrion;
Biological process	response to organic cyclic compound; branched-chain amino acid catabolic process; metanephric proximal convoluted tubule development; ketone body biosynthetic process; brain development; response to starvation; response to hormone; liver development; adipose tissue development; metabolism; protein homooligomerization; acetyl-CoA catabolic process; coenzyme A metabolic process; fatty acid beta-oxidation; coenzyme A biosynthetic process; acetyl-CoA biosynthetic process; ketone body catabolic process; isoleucine catabolic process; propionyl-CoA biosynthetic process; ketone body metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	38
	110446
	ENSG00000075239
	ENSMUSG00000032047
	P24752
	Q8QZT1
	NM_000019
	NM_144784
	NP_000010
	NP_659033
	Wikidata
View/Edit Human	View/Edit Mouse

Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT1 (Acetyl-Coenzyme A acetyltransferase 1) gene.

Acetyl-Coenzyme A acetyltransferase 1 is an acetyl-CoA C-acetyltransferase enzyme.