Aminocarboxymuconate-semialdehyde decarboxylase
| aminocarboxymuconate-semialdehyde decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
aminocarboxymuconate-semialdehyde decarboxylase dimer, Human | |||||||||
| Identifiers | |||||||||
| EC no. | 4.1.1.45 | ||||||||
| CAS no. | 37289-47-7 | ||||||||
| Alt. names | ACMSD | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The enzyme aminocarboxymuconate-semialdehyde decarboxylase (EC 4.1.1.45) catalyzes the chemical reaction
- 2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate 2-aminomuconate semialdehyde + CO2
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. This enzyme participates in tryptophan metabolism. It has been identified as a marker in nonverbal autism.