ACSBG1

ACSBG1
Identifiers
Aliases	ACSBG1, BG, BG1, BGM, GR-LACS, LPD, acyl-CoA synthetase bubblegum family member 1
External IDs	OMIM: 614362; MGI: 2385656; HomoloGene: 9044; GeneCards: ACSBG1; OMA:ACSBG1 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	78,245,688 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	54,569,154 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; inferior olivary nucleus; ; C1 segment; ; dorsal motor nucleus of vagus nerve; ; endothelial cell; ; internal globus pallidus; ; putamen; ; caudate nucleus; ; skin of arm; ; substantia nigra;
	Top expressed in
	lip; ; cerebellar cortex; ; deep cerebellar nuclei; ; adrenal gland; ; skin of external ear; ; visual cortex; ; esophagus; ; lobe of cerebellum; ; superior frontal gyrus; ; primary visual cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; ligase activity; catalytic activity; ATP binding; decanoate-CoA ligase activity; long-chain fatty acid-CoA ligase activity; very long-chain fatty acid-CoA ligase activity;
Cellular component	cytosol; intracellular membrane-bounded organelle; endoplasmic reticulum; cytoplasmic vesicle; cytoplasm;
Biological process	lipid metabolism; very long-chain fatty acid metabolic process; response to glucocorticoid; fatty acid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; myelination; metabolism; long-chain fatty acid metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	23205
	94180
	ENSG00000103740
	ENSMUSG00000032281
	Q96GR2
	Q99PU5
	NM_001199377; NM_015162
	NM_053178
	NP_001186306; NP_055977
	NP_444408
	Wikidata
View/Edit Human	View/Edit Mouse

Acyl-CoA Synthetase, Bubblegum Family, member 1 (ACSBG1) is an enzyme that in humans is encoded by the ACSBG1 gene.

The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. The conversion of long chain fatty acids into long chain acyl-CoAs in mice is catalysed by ACSBG1.