ACSL3

ACSL3
Identifiers
Aliases	ACSL3, ACS3, FACL3, PRO2194, acyl-CoA synthetase long-chain family member 3, acyl-CoA synthetase long chain family member 3, LACS3, LACS 3
External IDs	OMIM: 602371; MGI: 1921455; HomoloGene: 3278; GeneCards: ACSL3; OMA:ACSL3 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	222,944,639 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	78,685,460 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; lateral nuclear group of thalamus; ; Brodmann area 23; ; Brodmann area 10; ; Brodmann area 46; ; cartilage tissue; ; frontal pole; ; postcentral gyrus; ; pars compacta; ; pars reticulata;
	Top expressed in
	otolith organ; ; utricle; ; neural layer of retina; ; medial dorsal nucleus; ; epithelium of small intestine; ; medial geniculate nucleus; ; suprachiasmatic nucleus; ; spermatocyte; ; deep cerebellar nuclei; ; ventral tegmental area;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein domain specific binding; ligase activity; catalytic activity; ATP binding; protein kinase binding; long-chain fatty acid-CoA ligase activity; decanoate-CoA ligase activity;
Cellular component	organelle membrane; integral component of membrane; Golgi apparatus; endoplasmic reticulum membrane; membrane; intracellular membrane-bounded organelle; lipid droplet; peroxisomal membrane; peroxisome; mitochondrial outer membrane; endoplasmic reticulum; mitochondrion; perinuclear region of cytoplasm;
Biological process	positive regulation of Golgi to plasma membrane protein transport; response to organic cyclic compound; response to nutrient; lipid metabolism; fatty acid metabolic process; brain development; fatty acid biosynthetic process; long-chain fatty-acyl-CoA biosynthetic process; positive regulation of secretion; long-chain fatty acid import into cell; very-low-density lipoprotein particle assembly; metabolism; long-chain fatty acid metabolic process; positive regulation of phosphatidylcholine biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	2181
	74205
	ENSG00000123983
	ENSMUSG00000032883
	O95573
	Q9CZW4
	NM_004457; NM_203372; NM_001354158; NM_001354159
	NM_001033606; NM_001136222; NM_028817
	NP_004448; NP_976251; NP_001341087; NP_001341088
	NP_001028778; NP_001129694; NP_083093
	Wikidata
View/Edit Human	View/Edit Mouse

Long-chain-fatty-acid—CoA ligase 3 is an enzyme that in humans is encoded by the ACSL3 gene.