ACTG2

ACTG2
Identifiers
Aliases	ACTG2, ACT, ACTA3, ACTE, ACTL3, ACTSG, VSCM, actin, gamma 2, smooth muscle, enteric, actin gamma 2, smooth muscle, VSCM1, MMIHS5
External IDs	OMIM: 102545; MGI: 104589; HomoloGene: 123845; GeneCards: ACTG2; OMA:ACTG2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	73,919,865 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	83,513,247 bp
RNA expression pattern
	Top expressed in
	seminal vesicula; ; tail of epididymis; ; saphenous vein; ; muscle layer of sigmoid colon; ; gastric mucosa; ; popliteal artery; ; tibial arteries; ; prostate; ; myometrium; ; urethra;
	Top expressed in
	umbilical cord; ; migratory enteric neural crest cell; ; cervix; ; left colon; ; ileum; ; seminal vesicula; ; pyloric antrum; ; seminiferous tubule; ; gallbladder; ; esophagus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; ATP binding;
Cellular component	cytoplasm; filopodium; cell body; myosin filament; cytosol; blood microparticle; extracellular exosome; cytoskeleton; cell periphery; lamellipodium; extracellular space;
Biological process	mesenchyme migration; positive regulation of gene expression; muscle contraction;
	Sources:Amigo / QuickGO
Orthologs
	72
	11468
	ENSG00000163017
	ENSMUSG00000059430
	P63267
	P63268
	NM_001615; NM_001199893
	NM_009610
	NP_001186822; NP_001606
	NP_033740
	Wikidata
View/Edit Human	View/Edit Mouse

Actin, gamma-enteric smooth muscle is a protein that in humans is encoded by the ACTG2 gene.

Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 2, encoded by this gene, is a smooth muscle actin found in enteric tissues.