ADAM15

ADAM15
Identifiers
Aliases	ADAM15, MDC15, ADAM metallopeptidase domain 15
External IDs	OMIM: 605548; MGI: 1333882; HomoloGene: 2829; GeneCards: ADAM15; OMA:ADAM15 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	155,062,775 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	89,257,303 bp
RNA expression pattern
	Top expressed in
	skin of leg; ; skin of abdomen; ; apex of heart; ; tibial nerve; ; left uterine tube; ; gastric mucosa; ; minor salivary glands; ; upper lobe of left lung; ; right lung; ; olfactory zone of nasal mucosa;
	Top expressed in
	granulocyte; ; lip; ; superior frontal gyrus; ; gastrula; ; gallbladder; ; superior surface of tongue; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; esophagus; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	SH3 domain binding; metal ion binding; integrin binding; peptidase activity; protein binding; hydrolase activity; metallopeptidase activity; metalloendopeptidase activity;
Cellular component	integral component of membrane; cell projection; membrane; adherens junction; plasma membrane; cell surface; cell junction; acrosomal vesicle; extracellular exosome; cytoplasmic vesicle; endomembrane system; motile cilium; cilium;
Biological process	male gonad development; negative regulation of receptor binding; tissue regeneration; extracellular matrix disassembly; proteolysis; negative regulation of cell-matrix adhesion; negative regulation of cell migration; cell adhesion; negative regulation of cell growth; angiogenesis; collagen catabolic process; integrin-mediated signaling pathway; cell-matrix adhesion; innate immune response; cardiac epithelial to mesenchymal transition; apoptotic process; extracellular matrix organization; immune response to tumor cell; cellular response to phorbol 13-acetate 12-myristate; response to hypobaric hypoxia;
	Sources:Amigo / QuickGO
Orthologs
	8751
	11490
	ENSG00000143537
	ENSMUSG00000028041
	Q13444
	O88839
NM_001261464; NM_001261465; NM_001261466; NM_003815; NM_207191;
	NM_207194; NM_207195; NM_207196; NM_207197
	NM_001037722; NM_009614
NP_001248393; NP_001248394; NP_001248395; NP_003806; NP_997074;
	NP_997077; NP_997078; NP_997079; NP_997080
	NP_001032811; NP_033744
	Wikidata
View/Edit Human	View/Edit Mouse

Disintegrin and metalloproteinase domain-containing protein 15 is an enzyme that in humans is encoded by the ADAM15 gene.