ADAM2

ADAM2
Identifiers
Aliases	ADAM2, CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30, PH30-beta, ADAM metallopeptidase domain 2
External IDs	OMIM: 601533; MGI: 1340894; HomoloGene: 1127; GeneCards: ADAM2; OMA:ADAM2 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	39,838,227 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	66,315,182 bp
RNA expression pattern
	Top expressed in
	testicle; ; left testis; ; right testis; ; testicle; ; gonad; ; placenta; ; myeloid leukocyte; ; monocyte; ; prostate; ; appendix;
	Top expressed in
	spermatocyte; ; spermatid; ; seminiferous tubule; ; morula; ; blastocyst; ; duodenum; ; neural tube; ; endocrine system; ; islet of Langerhans; ; digastric muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	integrin binding; metalloendopeptidase activity; metallopeptidase activity;
Cellular component	integral component of membrane; cell surface; plasma membrane; integral component of plasma membrane; membrane; protein-containing complex;
Biological process	visual learning; fusion of sperm to egg plasma membrane involved in single fertilization; cell adhesion; adult behavior; proteolysis; binding of sperm to zona pellucida; single fertilization; positive regulation of gene expression;
	Sources:Amigo / QuickGO
Orthologs
	2515
	11495
	ENSG00000104755; ENSG00000276286
	ENSMUSG00000022039
	Q99965
	Q60718
	NM_001278113; NM_001278114; NM_001464
	NM_009618
	NP_001265042; NP_001265043; NP_001455
	NP_033748
	Wikidata
View/Edit Human	View/Edit Mouse

Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin is an enzyme that in humans is encoded by the ADAM2 gene.