ADAMTS5

ADAMTS5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2RJQ, 3B8Z, 3HY7, 3HY9, 3HYG, 3LJT
Identifiers
Aliases	ADAMTS5, ADAM-TS 11, ADAM-TS 5, ADAM-TS5, ADAMTS-11, ADAMTS-5, ADAMTS11, ADMP-2, ADAM metallopeptidase with thrombospondin type 1 motif 5
External IDs	OMIM: 605007; MGI: 1346321; HomoloGene: 5109; GeneCards: ADAMTS5; OMA:ADAMTS5 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	26,967,088 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	85,698,716 bp
RNA expression pattern
	Top expressed in
	lactiferous duct; ; synovial joint; ; stromal cell of endometrium; ; skin of hip; ; decidua; ; synovial membrane; ; Epithelium of choroid plexus; ; endothelial cell; ; buccal mucosa cell; ; gastric mucosa;
	Top expressed in
	decidua; ; gastrula; ; stroma of bone marrow; ; white adipose tissue; ; aortic valve; ; ascending aorta; ; sciatic nerve; ; iris; ; efferent ductule; ; trigeminal ganglion;
	More reference expression data
	n/a
Gene ontology
Molecular function	heparin binding; zinc ion binding; extracellular matrix binding; metal ion binding; integrin binding; peptidase activity; protein binding; hydrolase activity; metallopeptidase activity; metalloendopeptidase activity;
Cellular component	endoplasmic reticulum lumen; extracellular region; extracellular space; extracellular matrix; collagen-containing extracellular matrix;
Biological process	extracellular matrix disassembly; proteolysis; defense response to bacterium; tooth eruption; negative regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	11096
	23794
	ENSG00000154736
	ENSMUSG00000022894
	Q9UNA0
	Q9R001
	NM_007038
	NM_011782
	NP_008969
	NP_035912
	Wikidata
View/Edit Human	View/Edit Mouse

A disintegrin and metalloproteinase with thrombospondin motifs 5 also known as ADAMTS5 is an enzyme that in humans is encoded by the ADAMTS5 gene.