ADAMTS8

ADAMTS8
Identifiers
Aliases	ADAMTS8, ADAM-TS8, METH2, ADAM metallopeptidase with thrombospondin type 1 motif 8
External IDs	OMIM: 605175; MGI: 1353468; HomoloGene: 5108; GeneCards: ADAMTS8; OMA:ADAMTS8 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	130,428,609 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	30,875,134 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; upper lobe of left lung; ; endothelial cell; ; lower lobe of lung; ; right lung; ; Brodmann area 23; ; entorhinal cortex; ; tail of epididymis; ; right coronary artery; ; visceral pleura;
	Top expressed in
	tunica media of zone of aorta; ; lumbar spinal ganglion; ; soleus muscle; ; ankle; ; atrium; ; internal carotid artery; ; endocardial cushion; ; semi-lunar valve; ; inner muscle layer; ; tunica adventitia of aorta;
	More reference expression data
	n/a
Gene ontology
Molecular function	integrin binding; zinc ion binding; peptidase activity; metalloendopeptidase activity; heparin binding; low-affinity phosphate transmembrane transporter activity; metallopeptidase activity; hydrolase activity; metal ion binding;
Cellular component	extracellular region; extracellular matrix; collagen-containing extracellular matrix;
Biological process	proteolysis; negative regulation of cell population proliferation; phosphate ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	11095
	30806
	ENSG00000134917
	ENSMUSG00000031994
	Q9UP79
	P57110
	NM_007037
	NM_013906; NM_001326292
	NP_008968
	NP_038934.2
	Wikidata
View/Edit Human	View/Edit Mouse

A disintegrin and metalloproteinase with thrombospondin motifs 8 is an enzyme that in humans is encoded by the ADAMTS8 gene.