ADD2

ADD2
Identifiers
Aliases	ADD2, ADDB, adducin 2
External IDs	OMIM: 102681; MGI: 87919; HomoloGene: 1221; GeneCards: ADD2; OMA:ADD2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	70,768,225 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	86,101,391 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; middle temporal gyrus; ; Brodmann area 23; ; paraflocculus of cerebellum; ; frontal pole; ; Region I of hippocampus proper; ; postcentral gyrus; ; Brodmann area 46; ; entorhinal cortex; ; superior frontal gyrus;
	Top expressed in
	olfactory tubercle; ; Region I of hippocampus proper; ; piriform cortex; ; dentate gyrus; ; facial motor nucleus; ; central gray substance of midbrain; ; dentate gyrus of hippocampal formation granule cell; ; subiculum; ; pontine nuclei; ; visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	spectrin binding; protein homodimerization activity; structural molecule activity; calmodulin binding; actin filament binding; protein heterodimerization activity; actin binding; protein kinase binding;
Cellular component	F-actin capping protein complex; cytoplasm; cytosol; membrane; plasma membrane; cytoskeleton; postsynaptic density; cytoplasmic vesicle; plasma membrane raft;
Biological process	barbed-end actin filament capping; actin filament bundle assembly; transmembrane transport; positive regulation of protein binding; actin cytoskeleton organization; leukocyte migration; leukocyte tethering or rolling; protein-containing complex assembly; hemopoiesis; synapse assembly;
	Sources:Amigo / QuickGO
Orthologs
	119
	11519
	ENSG00000075340
	ENSMUSG00000030000
	P35612
	Q9QYB8
NM_001185054; NM_001185055; NM_001617; NM_017482; NM_017483;
	NM_017484; NM_017485; NM_017486; NM_017487; NM_017488
NM_001271857; NM_001271858; NM_001271859; NM_001271860; NM_001271861;
	NM_013458
	NP_001171983; NP_001171984; NP_001608; NP_059516; NP_059522
NP_001258786; NP_001258787; NP_001258788; NP_001258789; NP_001258790;
	NP_038486
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-adducin is a protein that in humans is encoded by the ADD2 gene.