GPR128

ADGRG7
Identifiers
Aliases	ADGRG7, GPR128, adhesion G protein-coupled receptor G7
External IDs	OMIM: 612307; MGI: 2441732; HomoloGene: 13115; GeneCards: ADGRG7; OMA:ADGRG7 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	100,695,479 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	56,616,218 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; testicle; ; right lobe of liver; ; mucosa of transverse colon; ; gonad; ; rectum; ; gallbladder; ; smooth muscle tissue; ; appendix;
	Top expressed in
	jejunum; ; ileum; ; colon; ; duodenum; ; spermatid; ; uterus; ; yolk sac; ; ovary; ; embryo; ; granulocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; protein binding; transmembrane signaling receptor activity; signal transducer activity;
Cellular component	integral component of membrane; membrane; intracellular anatomical structure; integral component of plasma membrane;
Biological process	G protein-coupled receptor signaling pathway; cell surface receptor signaling pathway; signal transduction; adenylate cyclase-activating G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	84873
	239853
	ENSG00000144820
	ENSMUSG00000022755
	Q96K78
	Q8BM96
	NM_001308362; NM_032787
	NM_172825
	NP_001295291; NP_116176
	NP_766413
	Wikidata
View/Edit Human	View/Edit Mouse

G protein-coupled receptor 128 is a protein encoded by the ADGRG7 gene. GPR128 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.